Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway
In mammalian embryonic stem cells, the acquisition of pluripotency is dependent on Nanog, but the in vivo analysis of Nanog has been hampered by its requirement for early mouse development. In an effort to examine the role of Nanog in vivo, we identified a zebrafish Nanog ortholog and found that its...
Main Authors: | Xu, Cong, Fan, Zi Peng, Fogley, Rachel, DiBiase, Anthony, Trompouki, Eirini, Unternaehrer, Juli, Xiong, Fengzhu, Torregroza, Ingrid, Evans, Todd, Megason, Sean G., Daley, George Q., Schier, Alexander F., Young, Richard A., Zon, Leonard I., Muller, Patrick, Young, Richard A. |
---|---|
Other Authors: | Massachusetts Institute of Technology. Computational and Systems Biology Program |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2014
|
Online Access: | http://hdl.handle.net/1721.1/91520 https://orcid.org/0000-0001-8855-8647 |
Similar Items
-
Both Nodal signalling and stochasticity select for prospective distal visceral endoderm in mouse embryos
by: Katsuyoshi Takaoka, et al.
Published: (2017-11-01) -
Nodal dependent differential localisation of dishevelled-2 demarcates regions of differing cell behaviour in the visceral endoderm
by: Trichas, G, et al.
Published: (2011) -
Nodal dependent differential localisation of dishevelled-2 demarcates regions of differing cell behaviour in the visceral endoderm.
by: Georgios Trichas, et al.
Published: (2011-02-01) -
Attenuation of Notch and Hedgehog signaling is required for fate specification in the spinal cord.
by: Peng Huang, et al.
Published: (2012-01-01) -
Eleven daughters of NANOG.
by: Booth, H, et al.
Published: (2004)