A novel Netrin-1-sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching

Developmental axon branching dramatically increases synaptic capacity and neuronal surface area. Netrin-1 promotes branching and synaptogenesis, but the mechanism by which Netrin-1 stimulates plasma membrane expansion is unknown. We demonstrate that SNARE-mediated exocytosis is a prerequisite for ax...

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Bibliographic Details
Main Authors: McClain, Leslie Marie, Winkle, Cortney C., Valtschanoff, Juli G., Park, Charles S., Maglione, Christopher, Gupton, Stephanie L.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Rockefeller University Press, The 2014
Online Access:http://hdl.handle.net/1721.1/91533
https://orcid.org/0000-0001-6738-2435