Redesign of a Dioxygenase in Morphine Biosynthesis

Opium poppy (Papaver somniferum) produces medicinally important benzylisoquinoline alkaloids, including the analgesics codeine and morphine, in the morphinan pathway. We aligned three dioxygenases that were recently discovered in P. somniferum and subsequently identified the nonconserved regions. Tw...

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书目详细资料
Main Authors: Runguphan, Weerawat, Glenn, Weslee S., O'Connor, Sarah Ellen
其他作者: Massachusetts Institute of Technology. Department of Chemistry
格式: 文件
语言:en_US
出版: Elsevier 2014
在线阅读:http://hdl.handle.net/1721.1/91546