Composite RNAi-Microsponges Form through Self-Assembly of the Organic and Inorganic Products of Transcription

Inorganic nanostructures have been used extensively to package nucleic acids into forms useful for therapeutic applications. Here we report that the two products of transcription, RNA and inorganic pyrophosphate, can self-assemble to form composite microsponge structures composed of nanocrystalline...

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Bibliographic Details
Main Authors: Roh, Young Hoon, Deng, Zhou J., Shopsowitz, Kevin, Morton, Stephen Winford, Hammond, Paula T
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Wiley Blackwell 2014
Online Access:http://hdl.handle.net/1721.1/91594
https://orcid.org/0000-0003-3988-0837