Vaccine delivery with microneedle skin patches in nonhuman primates

Transcutaneous drug delivery from planar skin patches is effective for small-molecule drugs and skin-permeable vaccine adjuvants. However, to achieve efficient delivery of vaccines and other macromolecular therapeutics into the skin, penetration of the stratum corneum is needed. Topically applied sk...

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Bibliographic Details
Main Authors: Li, Adrienne Victoria, Abbink, Peter, Liu, Jinyan, Li, Hualin, Stanley, Kelly A., Smith, Kaitlin M., Lavine, Christy L., Seaman, Michael S., Kramer, Joshua A., Miller, Andrew D., Abraham, Wuhbet, Suh, Heikyung, Elkhader, Jamal, Barouch, Dan H., DeMuth, Peter Charles, Irvine, Darrell J., Hammond, Paula T.
Other Authors: Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies
Format: Article
Language:en_US
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/1721.1/91599
https://orcid.org/0000-0003-0787-298X