Vaccine delivery with microneedle skin patches in nonhuman primates

Transcutaneous drug delivery from planar skin patches is effective for small-molecule drugs and skin-permeable vaccine adjuvants. However, to achieve efficient delivery of vaccines and other macromolecular therapeutics into the skin, penetration of the stratum corneum is needed. Topically applied sk...

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Main Authors: Li, Adrienne Victoria, Abbink, Peter, Liu, Jinyan, Li, Hualin, Stanley, Kelly A., Smith, Kaitlin M., Lavine, Christy L., Seaman, Michael S., Kramer, Joshua A., Miller, Andrew D., Abraham, Wuhbet, Suh, Heikyung, Elkhader, Jamal, Barouch, Dan H., DeMuth, Peter Charles, Irvine, Darrell J., Hammond, Paula T.
其他作者: Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies
格式: 文件
语言:en_US
出版: Nature Publishing Group 2014
在线阅读:http://hdl.handle.net/1721.1/91599
https://orcid.org/0000-0003-0787-298X