Vaccine delivery with microneedle skin patches in nonhuman primates
Transcutaneous drug delivery from planar skin patches is effective for small-molecule drugs and skin-permeable vaccine adjuvants. However, to achieve efficient delivery of vaccines and other macromolecular therapeutics into the skin, penetration of the stratum corneum is needed. Topically applied sk...
Main Authors: | Li, Adrienne Victoria, Abbink, Peter, Liu, Jinyan, Li, Hualin, Stanley, Kelly A., Smith, Kaitlin M., Lavine, Christy L., Seaman, Michael S., Kramer, Joshua A., Miller, Andrew D., Abraham, Wuhbet, Suh, Heikyung, Elkhader, Jamal, Barouch, Dan H., DeMuth, Peter Charles, Irvine, Darrell J., Hammond, Paula T. |
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Other Authors: | Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2014
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Online Access: | http://hdl.handle.net/1721.1/91599 https://orcid.org/0000-0003-0787-298X |
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