A Nonpolycationic Fully Proteinaceous Multiagent System for Potent Targeted Delivery of siRNA

Protein-based methods of targeted short-interfering RNA (siRNA) delivery have the potential to solve some of the problems faced by nanoparticle-based methods, such as poor pharmacokinetics and biodistribution, low tumor penetration, and polydispersity. However, protein-based targeted delivery has be...

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Bibliographic Details
Main Authors: Liu, David V., Yang, Nicole Jie Yeon, Wittrup, Karl Dane
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: 2014
Online Access:http://hdl.handle.net/1721.1/91602
https://orcid.org/0000-0003-2398-5896
https://orcid.org/0000-0002-0882-7761