Grounded: Transcriptional Pausing in Naive mESCs

Growing mouse pluripotent stem cells in defined media with signaling inhibitors establishes a naive ground state different from that of cells grown in serum. Recently in Cell, Marks et al. (2012) reported differences in the transcriptional and epigenomic landscapes of naive and serum-exposed mouse s...

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Bibliographic Details
Main Authors: Guenther, Matthew G., Young, Richard A., Young, Richard A.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/91606
https://orcid.org/0000-0001-8855-8647