Effect of Particle Diameter and Surface Composition on the Spontaneous Fusion of Monolayer-Protected Gold Nanoparticles with Lipid Bilayers

Anionic, monolayer-protected gold nanoparticles (AuNPs) have been shown to nondisruptively penetrate cellular membranes. Here, we show that a critical first step in the penetration process is potentially the fusion of such AuNPs with lipid bilayers. Free energy calculations, experiments on unilamell...

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Bibliographic Details
Main Authors: Van Lehn, Reid C., Atukorale, Prabhani U., Carney, Randy P., Yang, Yu-Sang Sabrina, Stellacci, Francesco, Irvine, Darrell J., Alexander-Katz, Alfredo
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2014
Online Access:http://hdl.handle.net/1721.1/91636
https://orcid.org/0000-0001-5554-1283