Effect of Particle Diameter and Surface Composition on the Spontaneous Fusion of Monolayer-Protected Gold Nanoparticles with Lipid Bilayers
Anionic, monolayer-protected gold nanoparticles (AuNPs) have been shown to nondisruptively penetrate cellular membranes. Here, we show that a critical first step in the penetration process is potentially the fusion of such AuNPs with lipid bilayers. Free energy calculations, experiments on unilamell...
Main Authors: | Van Lehn, Reid C., Atukorale, Prabhani U., Carney, Randy P., Yang, Yu-Sang Sabrina, Stellacci, Francesco, Irvine, Darrell J., Alexander-Katz, Alfredo |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society (ACS)
2014
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Online Access: | http://hdl.handle.net/1721.1/91636 https://orcid.org/0000-0001-5554-1283 |
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