Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks

Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks

Crosstalk and complexity within signaling pathways and their perturbation by oncogenes limit component-by-component approaches to understanding human disease. Network analysis of how normal and oncogenic signaling can be rewired by drugs may provide opportunities to target tumors with high specifici...

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Bibliographic Details
Main Authors: Lee, Michael J., Ye, Albert S., Gardino, Alexandra Kate, Heijink, Anne Margriet, Sorger, Peter K., MacBeath, Gavin, Yaffe, Michael B., Sorger, Peter K., Yaffe, Michael B.
Other Authors: Massachusetts Institute of Technology. Cell Decision Process Center
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/91688
https://orcid.org/0000-0002-9547-3251

Internet

http://hdl.handle.net/1721.1/91688
https://orcid.org/0000-0002-9547-3251

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