The C-Terminal Domain of Eukaryotic Initiation Factor 5 Promotes Start Codon Recognition by Its Dynamic Interplay with eIF1 and eIF2β

The C-Terminal Domain of Eukaryotic Initiation Factor 5 Promotes Start Codon Recognition by Its Dynamic Interplay with eIF1 and eIF2β

Recognition of the proper start codon on mRNAs is essential for protein synthesis, which requires scanning and involves eukaryotic initiation factors (eIFs) eIF1, eIF1A, eIF2, and eIF5. The carboxyl terminal domain (CTD) of eIF5 stimulates 43S preinitiation complex (PIC) assembly; however, its preci...

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Главные авторы: Luna, Rafael E., Arthanari, Haribabu, Hiraishi, Hiroyuki, Nanda, Jagpreet, Martin-Marcos, Pilar, Markus, Michelle A., Akabayov, Barak, Milbradt, Alexander G., Luna, Lunet E., Seo, Hee-Chan, Hyberts, Sven G., Fahmy, Amr, Reibarkh, Mikhail, Miles, David, Hagner, Patrick R., O'Day, Elizabeth M., Yi, Tingfang, Marintchev, Assen, Hinnebusch, Alan G., Lorsch, Jon R., Asano, Katsura, Wagner, Gerhard
Другие авторы: Massachusetts Institute of Technology. Department of Chemical Engineering
Формат: Статья
Язык:en_US
Опубликовано: Elsevier 2014
Online-ссылка:http://hdl.handle.net/1721.1/91690

Internet

http://hdl.handle.net/1721.1/91690

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