Adaptive Mutations that Prevent Crosstalk Enable the Expansion of Paralogous Signaling Protein Families
Orthologous proteins often harbor numerous substitutions, but whether these differences result from neutral or adaptive processes is usually unclear. To tackle this challenge, we examined the divergent evolution of a model bacterial signaling pathway comprising the kinase PhoR and its cognate substr...
| Autors principals: | , , , |
|---|---|
| Altres autors: | |
| Format: | Article |
| Idioma: | en_US |
| Publicat: |
Elsevier B.V.
2014
|
| Accés en línia: | http://hdl.handle.net/1721.1/91691 https://orcid.org/0000-0002-8288-7607 |