DEPTOR Cell-Autonomously Promotes Adipogenesis, and Its Expression Is Associated with Obesity

DEPTOR Cell-Autonomously Promotes Adipogenesis, and Its Expression Is Associated with Obesity

DEP domain-containing mTOR-interacting protein (DEPTOR) inhibits the mechanistic target of rapamycin (mTOR), but its in vivo functions are unknown. Previous work indicates that Deptor is part of the Fob3a quantitative trait locus (QTL) linked to obesity/leanness in mice, with Deptor expression being...

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Bibliographic Details
Main Authors: Laplante, Mathieu, Horvat, Simon, Festuccia, William T., Birsoy, Kivanc, Prevorsek, Zala, Efeyan, Alejo, Sabatini, David M., Sabatini, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/91706
https://orcid.org/0000-0002-1446-7256

Internet

http://hdl.handle.net/1721.1/91706
https://orcid.org/0000-0002-1446-7256

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