mTOR Signaling in Growth Control and Disease

The mechanistic target of rapamycin (mTOR) signaling pathway senses and integrates a variety of environmental cues to regulate organismal growth and homeostasis. The pathway regulates many major cellular processes and is implicated in an increasing number of pathological conditions, including cancer...

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Bibliographic Details
Main Authors: Laplante, Mathieu, Sabatini, David M., Sabatini, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/91891
https://orcid.org/0000-0002-1446-7256