Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

During cellular reprogramming, only a small fraction of cells become induced pluripotent stem cells (iPSCs). Previous analyses of gene expression during reprogramming were based on populations of cells, impeding single-cell level identification of reprogramming events. We utilized two gene expressio...

ver descrição completa

Detalhes bibliográficos
Principais autores: Buganim, Yosef, Faddah, Dina A., Itskovich, Elena, Markoulaki, Styliani, Ganz, Kibibi, van Oudenaarden, Alexander, Jaenisch, Rudolf, Klemm, Sandy Lee, van Oudenaarden, Alexander, Cheng, Albert Wu
Outros Autores: Massachusetts Institute of Technology. Computational and Systems Biology Program
Formato: Artigo
Idioma:en_US
Publicado em: Elsevier 2014
Acesso em linha:http://hdl.handle.net/1721.1/91944

Internet

http://hdl.handle.net/1721.1/91944

Registros relacionados