Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

During cellular reprogramming, only a small fraction of cells become induced pluripotent stem cells (iPSCs). Previous analyses of gene expression during reprogramming were based on populations of cells, impeding single-cell level identification of reprogramming events. We utilized two gene expressio...

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Podrobná bibliografie
Hlavní autoři: Buganim, Yosef, Faddah, Dina A., Itskovich, Elena, Markoulaki, Styliani, Ganz, Kibibi, van Oudenaarden, Alexander, Jaenisch, Rudolf, Klemm, Sandy Lee, van Oudenaarden, Alexander, Cheng, Albert Wu
Další autoři: Massachusetts Institute of Technology. Computational and Systems Biology Program
Médium: Článek
Jazyk:en_US
Vydáno: Elsevier 2014
On-line přístup:http://hdl.handle.net/1721.1/91944

Internet

http://hdl.handle.net/1721.1/91944

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