Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

During cellular reprogramming, only a small fraction of cells become induced pluripotent stem cells (iPSCs). Previous analyses of gene expression during reprogramming were based on populations of cells, impeding single-cell level identification of reprogramming events. We utilized two gene expressio...

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Bibliographic Details
Main Authors: Buganim, Yosef, Faddah, Dina A., Itskovich, Elena, Markoulaki, Styliani, Ganz, Kibibi, van Oudenaarden, Alexander, Jaenisch, Rudolf, Klemm, Sandy Lee, van Oudenaarden, Alexander, Cheng, Albert Wu
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/91944

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