Rbfox2 controls autoregulation in RNA-binding protein networks

The tight regulation of splicing networks is critical for organismal development. To maintain robust splicing patterns, many splicing factors autoregulate their expression through alternative splicing-coupled nonsense-mediated decay (AS-NMD). However, as negative autoregulation results in a self-lim...

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Bibliographic Details
Main Authors: Boutz, Paul, Jangi, Mohini, Sharp, Phillip A., Paul, Prakriti
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2014
Online Access:http://hdl.handle.net/1721.1/91959
https://orcid.org/0000-0003-1465-1691