Identifying the Stem Cell of the Intestinal Crypt: Strategies and Pitfalls
Decades ago, two nonoverlapping crypt stem cell populations were proposed: Leblond’s Crypt Base Columnar (CBC) cell and Potten’s +4 cell. The identification of CBC markers including Lgr5 has confirmed Leblond’s predictions that CBC cells are anatomically distinct, long-lived stem cells that permanen...
| Main Authors: | , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Elsevier
2014
|
| Online Access: | http://hdl.handle.net/1721.1/91960 |