Polymerase exchange on single DNA molecules reveals processivity clamp control of translesion synthesis
Translesion synthesis (TLS) by Y-family DNA polymerases alleviates replication stalling at DNA damage. Ring-shaped processivity clamps play a critical but ill-defined role in mediating exchange between Y-family and replicative polymerases during TLS. By reconstituting TLS at the single-molecule leve...
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
National Academy of Sciences (U.S.)
2014
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| Online Access: | http://hdl.handle.net/1721.1/91963 https://orcid.org/0000-0001-7243-8261 |