Structure-based programming of lymph-node targeting in molecular vaccines

In cancer patients, visual identification of sentinel lymph nodes (LNs) is achieved by the injection of dyes that bind avidly to endogenous albumin, targeting these compounds to LNs, where they are efficiently filtered by resident phagocytes1, 2. Here we translate this ‘albumin hitchhiking’ approach...

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Bibliographic Details
Main Authors: Liu, Haipeng, Moynihan, Kelly Dare, Zheng, Yiran, Szeto, Gregory Lee, Li, Adrienne Victoria, Huang, Bonnie, Van Egeren, Debra S., Irvine, Darrell J., Lui, Haipeng, Park, Clara, S.M. Massachusetts Institute of Technology
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/1721.1/91972
https://orcid.org/0000-0003-1833-9822
https://orcid.org/0000-0001-7604-1333
https://orcid.org/0000-0003-0817-0525
https://orcid.org/0000-0002-4267-237X