Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing
Retrotransposons constitute a major source of genetic variation, and somatic retrotransposon insertions have been reported in cancer. Here, we applied TranspoSeq, a computational framework that identifies retrotransposon insertions from sequencing data, to whole genomes from 200 tumor/normal pairs a...
Main Authors: | , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Cold Spring Harbor Laboratory Press
2014
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Online Access: | http://hdl.handle.net/1721.1/91988 |