Molecular Signatures of Human Induced Pluripotent Stem Cells Highlight Sex Differences and Cancer Genes

Although human induced pluripotent stem cells (hiPSCs) have enormous potential in regenerative medicine, their epigenetic variability suggests that some lines may not be suitable for human therapy. There are currently few benchmarks for assessing quality. Here we show that X-inactivation markers can...

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Bibliographic Details
Main Authors: Anguera, Montserrat C., Sadreyev, Ruslan, Zhang, Zhaoqing, Szanto, Attila, Payer, Bernhard, Sheridan, Steven D., Kwok, Showming, Haggarty, Stephen J., Sur, Mriganka, Alvarez, Jason, Gimelbrant, Alexander A., Mitalipova, Maisam, Kirby, James E., Lee, Jeannie T.
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Elsevier B.V. 2014
Online Access:http://hdl.handle.net/1721.1/91999
https://orcid.org/0000-0003-2442-5671
https://orcid.org/0000-0002-3551-1244