High-Bandwidth AFM-Based Rheology Reveals that Cartilage is Most Sensitive to High Loading Rates at Early Stages of Impairment
Utilizing a newly developed atomic-force-microscopy-based wide-frequency rheology system, we measured the dynamic nanomechanical behavior of normal and glycosaminoglycan (GAG)-depleted cartilage, the latter representing matrix degradation that occurs at the earliest stages of osteoarthritis. We obse...
Main Authors: | , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Elsevier B.V.
2014
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Online Access: | http://hdl.handle.net/1721.1/92000 https://orcid.org/0000-0003-3511-5679 https://orcid.org/0000-0003-1970-9901 https://orcid.org/0000-0002-4942-3456 |