High-Bandwidth AFM-Based Rheology Reveals that Cartilage is Most Sensitive to High Loading Rates at Early Stages of Impairment

High-Bandwidth AFM-Based Rheology Reveals that Cartilage is Most Sensitive to High Loading Rates at Early Stages of Impairment

Utilizing a newly developed atomic-force-microscopy-based wide-frequency rheology system, we measured the dynamic nanomechanical behavior of normal and glycosaminoglycan (GAG)-depleted cartilage, the latter representing matrix degradation that occurs at the earliest stages of osteoarthritis. We obse...

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Bibliographic Details
Main Authors: Tavakoli Nia, Hadi, Soltani Bozchalooi, Iman, Li, Yang, Han, Lin, Hung, Han-Hwa K., Frank, Eliot, Youcef-Toumi, Kamal, Ortiz, Christine, Grodzinsky, Alan J.
Other Authors: Massachusetts Institute of Technology. Center for Biomedical Engineering
Format: Article
Language:en_US
Published: Elsevier B.V. 2014
Online Access:http://hdl.handle.net/1721.1/92000
https://orcid.org/0000-0003-3511-5679
https://orcid.org/0000-0003-1970-9901
https://orcid.org/0000-0002-4942-3456

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