Lineage Regulators Direct BMP and Wnt Pathways to Cell-Specific Programs during Differentiation and Regeneration

BMP and Wnt signaling pathways control essential cellular responses through activation of the transcription factors SMAD (BMP) and TCF (Wnt). Here, we show that regeneration of hematopoietic lineages following acute injury depends on the activation of each of these signaling pathways to induce expre...

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Bibliographic Details
Main Authors: Trompouki, Eirini, Bowman, Teresa V., Lawton, Lee N., Fan, Zi Peng, Wu, Dai-Chen, DiBiase, Anthony, Martin, Corey S., Cech, Jennifer N., Sessa, Anna K., Leblanc, Jocelyn L., Li, Pulin, Durand, Ellen M., Mosimann, Christian, Heffner, Garrett C., Daley, George Q., Paulson, Robert F., Young, Richard A., Zon, Leonard I.
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Elsevier B.V. 2014
Online Access:http://hdl.handle.net/1721.1/92051
https://orcid.org/0000-0001-8855-8647