Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations
Patient-specific induced pluripotent stem cells (iPSCs) derived from somatic cells provide a unique tool for the study of human disease, as well as a promising source for cell replacement therapies. One crucial limitation has been the inability to perform experiments under genetically defined condit...
Main Authors: | , , , , , , , , , , , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2014
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Online Access: | http://hdl.handle.net/1721.1/92247 https://orcid.org/0000-0003-1307-882X |