Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations

Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations

Patient-specific induced pluripotent stem cells (iPSCs) derived from somatic cells provide a unique tool for the study of human disease, as well as a promising source for cell replacement therapies. One crucial limitation has been the inability to perform experiments under genetically defined condit...

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Podrobná bibliografie
Hlavní autoři: Soldner, Frank, Hockemeyer, Dirk, Gao, Qing, Alagappan, Raaji, Khurana, Vikram, Golbe, Lawrence I., Myers, Richard H., Lindquist, Susan, Guschin, Dmitry, Fong, Lauren K., Vu, B. Joseph, Meng, Xiangdong, Urnov, Fyodor D., Rebar, Edward J., Gregory, Philip D., Zhang, H. Steve, Jaenisch, Rudolf, Laganiere, Josee, Zhang, Lei, Ph. D Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, fl. 2014., Cheng, Albert Wu
Další autoři: Massachusetts Institute of Technology. Computational and Systems Biology Program
Médium: Článek
Jazyk:en_US
Vydáno: Elsevier 2014
On-line přístup:http://hdl.handle.net/1721.1/92247
https://orcid.org/0000-0003-1307-882X

Internet

http://hdl.handle.net/1721.1/92247
https://orcid.org/0000-0003-1307-882X

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