mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

The nutrient- and growth factor-responsive kinase mTOR complex 1 (mTORC1) regulates many processes that control growth, including protein synthesis, autophagy, and lipogenesis. Through unknown mechanisms, mTORC1 promotes the function of SREBP, a master regulator of lipo- and sterolgenic gene transcr...

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Bibliographic Details
Main Authors: Peterson, Timothy R., Sengupta, Shomit S., Harris, Thurl E., Carpenter, Anne E., Kang, Seong A., Balderas, Eric, Guertin, David A., Madden, Katherine L., Finck, Brian N., Sabatini, David M., Peterson, Timothy Richard, Sengupta, Shomit, Sabatini, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/92259
https://orcid.org/0000-0002-1446-7256

Internet

http://hdl.handle.net/1721.1/92259
https://orcid.org/0000-0002-1446-7256

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