Mutations in MTFMT Underlie a Human Disorder of Formylation Causing Impaired Mitochondrial Translation

Mutations in MTFMT Underlie a Human Disorder of Formylation Causing Impaired Mitochondrial Translation

The metazoan mitochondrial translation machinery is unusual in having a single tRNA[superscript Met] that fulfills the dual role of the initiator and elongator tRNA[superscript Met]. A portion of the Met-tRNA[superscript Met] pool is formylated by mitochondrial methionyl-tRNA formyltransferase (MTFM...

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Main Authors: Tucker, Elena J., Hershman, Steven G., Belcher-Timme, Casey A., Patel, Jinal, Goldberger, Olga A., Christodoulou, John, Silberstein, Jonathon M., McKenzie, Matthew, Ryan, Michael T., Compton, Alison G., Jaffe, Jacob D., Carr, Steven A., Calvo, Sarah E., RajBhandary, Uttam L., Thorburn, David R., Mootha, Vamsi K., Koehrer, Caroline
其他作者: Massachusetts Institute of Technology. Department of Biology
格式: 文件
语言:en_US
出版: Elsevier 2014
在线阅读:http://hdl.handle.net/1721.1/92287
https://orcid.org/0000-0002-4530-5647

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http://hdl.handle.net/1721.1/92287
https://orcid.org/0000-0002-4530-5647

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