Effect of receptor binding domain mutations on receptor binding and transmissibility of avian influenza H5N1 viruses

Although H5N1 influenza viruses have been responsible for hundreds of human infections, these avian influenza viruses have not fully adapted to the human host. The lack of sustained transmission in humans may be due, in part, to their avian-like receptor preference. Here, we have introduced receptor...

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Bibliographic Details
Main Authors: Maines, Taronna R., Chen, Li-Mei, Van Hoeven, Neal, Tumpey, Terrence M., Blixt, Ola, Belser, Jessica A., Gustin, Kortney M., Pearce, Melissa B., Pappas, Claudia, Stevens, James, Cox, Nancy J., Paulson, James C., Raman, Rahul, Sasisekharan, Ram, Katz, Jacqueline M., Donis, Ruben O.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/92322
https://orcid.org/0000-0002-2085-7840