Dynamic Role of Cross-Linking Proteins in Actin Rheology

We develop a computational model to compare the relative importance of unbinding and unfolding of actin cross-linking proteins (ACPs) in the dynamic properties of the actin cytoskeleton. We show that in the strain-stiffening regime with typical physiological and experimental strain rates, unbinding...

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Bibliographic Details
Main Authors: Kim, Taeyoon, Hwang, Wonmuk, Kamm, Roger Dale
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/92328
https://orcid.org/0000-0002-7232-304X