Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
Cancer cells within individual tumors often exist in distinct phenotypic states that differ in functional attributes. While cancer cell populations typically display distinctive equilibria in the proportion of cells in various states, the mechanisms by which this occurs are poorly understood. Here,...
Main Authors: | Fillmore, Christine M., Jiang, Guozhi, Shapira, Sagi D., Tao, Kai, Kuperwasser, Charlotte, Gupta, Piyush, Lander, Eric Steven |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2014
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Online Access: | http://hdl.handle.net/1721.1/92332 https://orcid.org/0000-0002-9703-1780 |
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