C. elegans MCM-4 is a general DNA replication and checkpoint component with an epidermis-specific requirement for growth and viability

C. elegans MCM-4 is a general DNA replication and checkpoint component with an epidermis-specific requirement for growth and viability

DNA replication and its connection to M phase restraint are studied extensively at the level of single cells but rarely in the context of a developing animal. C. elegans lin-6 mutants lack DNA synthesis in postembryonic somatic cell lineages, while entry into mitosis continues. These mutants grow sl...

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Bibliographic Details
Main Authors: Korzelius, Jerome, The, Inge, Ruijtenberg, Suzan, Portegijs, Vincent, Xu, Huihong, van den Heuvel, Sander, Horvitz, Howard Robert
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/92333
https://orcid.org/0000-0002-9964-9613

Internet

http://hdl.handle.net/1721.1/92333
https://orcid.org/0000-0002-9964-9613

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