Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

The conserved Musashi (Msi) family of RNA binding proteins are expressed in stem/progenitor and cancer cells, but generally absent from differentiated cells, consistent with a role in cell state regulation. We found that Msi genes are rarely mutated but frequently overexpressed in human cancers and...

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Bibliographic Details
Main Authors: Katz, Yarden, Li, Feifei, Lambert, Nicole J., Tam, Wai-Leong, Airoldi, Edoardo M., Lengner, Christopher J., Yu, Zhengquan, Jaenisch, Rudolf, Sokol, Ethan Samuel, Cheng, Albert W., Gupta, Piyush, Burge, Christopher B
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: eLife Sciences Publications, Ltd. 2014
Online Access:http://hdl.handle.net/1721.1/92373
https://orcid.org/0000-0002-9703-1780
https://orcid.org/0000-0002-2988-0537