Chromatin Loops as Allosteric Modulators of Enhancer-Promoter Interactions
The classic model of eukaryotic gene expression requires direct spatial contact between a distal enhancer and a proximal promoter. Recent Chromosome Conformation Capture (3C) studies show that enhancers and promoters are embedded in a complex network of looping interactions. Here we use a polymer mo...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Public Library of Science
2014
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| Online Access: | http://hdl.handle.net/1721.1/92475 https://orcid.org/0000-0002-0785-5410 https://orcid.org/0000-0002-5320-2728 |