Diverse cell stresses induce unique patterns of tRNA up- and down-regulation: tRNA-seq for quantifying changes in tRNA copy number

Emerging evidence points to roles for tRNA modifications and tRNA abundance in cellular stress responses. While isolated instances of stress-induced tRNA degradation have been reported, we sought to assess the effects of stress on tRNA levels at a systems level. To this end, we developed a next-gene...

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Bibliographic Details
Main Authors: Pang, Yan Ling Joy, Abo, Ryan, Levine, Stuart S., Dedon, Peter C
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Oxford University Press 2014
Online Access:http://hdl.handle.net/1721.1/92530
https://orcid.org/0000-0003-0011-3067