A novel mechanism for the establishment of sister chromatid cohesion by the ECO1 acetyltransferase
Cohesin complex mediates cohesion between sister chromatids, which promotes high-fidelity chromosome segregation. Eco1p acetylates the cohesin subunit Smc3p during S phase to establish cohesion. The current model posits that this Eco1p-mediated acetylation promotes establishment by abrogating the ab...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
American Society for Cell Biology
2015
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| Online Access: | http://hdl.handle.net/1721.1/92588 |