Modifications of Microvascular EC Surface Modulate Phototoxicity of a Porphycene anti-ICAM-1 Immunoconjugate; Therapeutic Implications

Modifications of Microvascular EC Surface Modulate Phototoxicity of a Porphycene anti-ICAM-1 Immunoconjugate; Therapeutic Implications

Inflammation and shear stress can upregulate expression of cellular adhesion molecules in endothelial cells (EC). The modified EC surface becomes a mediating interface between the circulating blood elements and the endothelium, and grants opportunity for immunotherapy. In photodynamic therapy (PDT),...

Full description

Bibliographic Details
Main Authors: Duran-Frigola, Miquel, Hernandez, Bryan, Nonell, Santi, Fosas, Elisabet, Santoma, Pablo, Llinas, Maria C., Ruiz-Gonzalez, Ruben, Sanchez-Garcia, David, Balcells-Camps, Mercedes, Edelman, Elazer R, Rosas, Elisabet Canyelles
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2015
Online Access:http://hdl.handle.net/1721.1/92822
https://orcid.org/0000-0002-7832-7156

Internet

http://hdl.handle.net/1721.1/92822
https://orcid.org/0000-0002-7832-7156

Similar Items