Vascular Regeneration by Local Growth Factor Release Is Self-Limited by Microvascular Clearance

Background— The challenge of angiogenesis science is that stable sustained vascular regeneration in humans has not been realized despite promising preclinical findings. We hypothesized that angiogenic therapies powerfully self-regulate by dynamically altering tissue characteristics. Induced neocapil...

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Bibliographic Details
Main Authors: Le, Kha N., Tzafriri, A. Rami, Hayward, Alison, Edelman, Elazer R., Hwang, Chao-Wei, Lovich, Mark A.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: American Heart Association 2015
Online Access:http://hdl.handle.net/1721.1/92826
https://orcid.org/0000-0002-7832-7156
https://orcid.org/0000-0002-5446-819X