Identification and Rescue of  -Synuclein Toxicity in Parkinson Patient-Derived Neurons

Identification and Rescue of  -Synuclein Toxicity in Parkinson Patient-Derived Neurons

The induced pluripotent stem (iPS) cell field holds promise for in vitro disease modeling. However, identifying innate cellular pathologies, particularly for age-related neurodegenerative diseases, has been challenging. Here, we exploited mutation correction of iPS cells and conserved proteotoxic me...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Chung, Chee Yeun, Khurana, Vikram, Auluck, Pavan K., Tardiff, Daniel F., Mazzulli, Joseph R., Soldner, Frank, Baru, Valeriya, Lou, Yali, Freyzon, Yelena, Cho, Sukhee, Muffat, Julien, Mitalipova, Maisam, Pluth, Michael D., Jui, Nathan T., Schule, Birgitt, Lippard, Stephen J., Tsai, Li-Huei, Krainc, Dimitri, Jaenisch, Rudolf, Lindquist, Susan, Mungenast, Alison, Buchwald, Stephen Leffler
مؤلفون آخرون: Massachusetts Institute of Technology. Department of Biology
التنسيق: مقال
اللغة:en_US
منشور في: American Association for the Advancement of Science (AAAS) 2015
الوصول للمادة أونلاين:http://hdl.handle.net/1721.1/92886
https://orcid.org/0000-0002-2693-4982
https://orcid.org/0000-0003-1262-0592
https://orcid.org/0000-0003-1307-882X
https://orcid.org/0000-0003-3875-4775

الانترنت

http://hdl.handle.net/1721.1/92886
https://orcid.org/0000-0002-2693-4982
https://orcid.org/0000-0003-1262-0592
https://orcid.org/0000-0003-1307-882X
https://orcid.org/0000-0003-3875-4775

مواد مشابهة