A hippocampal Cdk5 pathway regulates extinction of contextual fear

Treatment of emotional disorders involves the promotion of extinction processes, which are defined as the learned reduction of fear. The molecular mechanisms underlying extinction have only begun to be elucidated. By employing genetic and pharmacological approaches in mice, we show here that extinct...

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Bibliographic Details
Main Authors: Sananbenesi, Farahnaz, Fischer, Andre, Wang, Xinyu, Schrick, Christina, Neve, Rachael L., Radulovic, Jelena, Tsai, Li-Huei
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Nature Publishing Group 2015
Online Access:http://hdl.handle.net/1721.1/92951
https://orcid.org/0000-0003-1262-0592