Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes

Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes

We developed modified RBCs to serve as carriers for systemic delivery of a wide array of payloads. These RBCs contain modified proteins on their plasma membrane, which can be labeled in a sortase-catalyzed reaction under native conditions without inflicting damage to the target membrane or cell. Sor...

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Bibliographic Details
Main Authors: Shi, Jiahai, Kundrat, Lenka, Pishesha, Novalia, Bilate, Angelina M., Theile, Christopher S., Maruyama, Takeshi, Dougan, Stephanie K., Ploegh, Hidde, Lodish, Harvey F.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2015
Online Access:http://hdl.handle.net/1721.1/93751
https://orcid.org/0000-0002-7029-7415
https://orcid.org/0000-0002-1090-6071
https://orcid.org/0000-0001-9306-8271

Internet

http://hdl.handle.net/1721.1/93751
https://orcid.org/0000-0002-7029-7415
https://orcid.org/0000-0002-1090-6071
https://orcid.org/0000-0001-9306-8271

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