Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome

Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome

Rett Syndrome is a neurodevelopmental disorder that arises from mutations in the X-linked gene methyl-CpG binding protein 2 (MeCP2). MeCP2 has a large number of targets and a wide range of functions, suggesting the hypothesis that functional signaling mechanisms upstream of synaptic and circuit matu...

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Bibliographic Details
Main Authors: Garcia, Rodrigo, Castro, Jorge, Kwok, Showming, Banerjee, Abhishek, Petravicz, Jeremy C., Woodson, Jonathan, Mellios, Nikolaos, Tropea, Daniela, Sur, Mriganka
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2015
Online Access:http://hdl.handle.net/1721.1/93790
https://orcid.org/0000-0003-2442-5671
https://orcid.org/0000-0001-9403-8787
https://orcid.org/0000-0001-9730-6636

Internet

http://hdl.handle.net/1721.1/93790
https://orcid.org/0000-0003-2442-5671
https://orcid.org/0000-0001-9403-8787
https://orcid.org/0000-0001-9730-6636

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