Palladium-catalyzed coupling of functionalized primary and secondary amines with aryl and heteroaryl halides: two ligands suffice in most cases

We report our studies on the use of two catalyst systems, based on the ligands BrettPhos and RuPhos, which provide the widest scope for Pd-catalyzed C–N cross-coupling reactions to date. Often low catalyst loadings and short reaction times can be used with functionalized aryl and heteroaryl coupling...

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Main Authors: Maiti, Debabrata, Fors, Brett P., Henderson, Jaclyn L., Nakamura, Yoshinori, Buchwald, Stephen Leffler
其他作者: Massachusetts Institute of Technology. Department of Chemistry
格式: 文件
语言:en_US
出版: Royal Society of Chemistry, The 2015
在线阅读:http://hdl.handle.net/1721.1/94326
https://orcid.org/0000-0003-3875-4775