Synthesis of Solid 2-Pyridylzinc Reagents and Their Application in Negishi Reactions
In search of alternatives to unstable or unreliable 2-pyridylboron reagents, we have explored two new varieties of solid, moderately air-stable 2-pyridylzinc reagents. Both reagents can be manipulated in air and are competent nucleophiles in Negishi cross-coupling reactions.
Main Authors: | Bernhardt, Sebastian, Stathakis, Christos, Knochel, Paul, Colombe, James Robert, Buchwald, Stephen Leffler |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society (ACS)
2015
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Online Access: | http://hdl.handle.net/1721.1/94497 https://orcid.org/0000-0002-8750-7968 https://orcid.org/0000-0003-3875-4775 |
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