Decreasing Herpes Simplex Viral Infectivity in Solution by Surface-Immobilized and Suspended N,N-Dodecyl,methyl-polyethylenimine

Purpose To explore surface-immobilized and suspended modalities of the hydrophobic polycation N,N-dodecyl,methyl-polyethylenimine (DMPEI) for the ability to reduce viral infectivity in aqueous solutions containing herpes simplex viruses (HSVs) 1 and 2. Methods Surface-immobilized (coated onto sur...

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Bibliographic Details
Main Authors: Larson, Alyssa Maxine, Oh, Hyung Suk, Knipe, David M., Klibanov, Alexander M.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Springer-Verlag 2015
Online Access:http://hdl.handle.net/1721.1/95420
https://orcid.org/0000-0003-3830-714X