Synergistic cytotoxicity of irinotecan and cisplatin in dual-drug targeted polymeric nanoparticles

Synergistic cytotoxicity of irinotecan and cisplatin in dual-drug targeted polymeric nanoparticles

Aim: Two unexplored aspects for irinotecan and cisplatin (I&C) combination chemotherapy are: actively targeting both drugs to a specific diseased cell type, and delivering both drugs on the same vehicle to ensure their synchronized entry into the cell at a well-defined ratio. In this work, the a...

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Bibliographic Details
Main Authors: Valencia, Pedro M, Pridgen, Eric M, Perea, Brian, Gadde, Suresh, Sweeney, Christopher, Kantoff, Philip W., Bander, Neil H., Langer, Robert, Lippard, Stephen J., Farokhzad, Omid C., Karnik, Rohit, Valencia, Pedro M., Pridgen, Eric M.
Other Authors: MIT-Harvard Center for Cancer Nanotechnology Excellence
Format: Article
Language:en_US
Published: Future Medicine 2015
Online Access:http://hdl.handle.net/1721.1/95422
https://orcid.org/0000-0003-0588-9286
https://orcid.org/0000-0002-2693-4982
https://orcid.org/0000-0002-2640-3006
https://orcid.org/0000-0003-4255-0492

Internet

http://hdl.handle.net/1721.1/95422
https://orcid.org/0000-0003-0588-9286
https://orcid.org/0000-0002-2693-4982
https://orcid.org/0000-0002-2640-3006
https://orcid.org/0000-0003-4255-0492

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