Bidentate Ligands on Osmium(VI) Nitrido Complexes Control Intracellular Targeting and Cell Death Pathways

The cellular response evoked by antiproliferating osmium(VI) nitrido compounds of general formula OsN(N[superscript N])Cl[subscript 3] (N[superscript N] = 2,2′-bipyridine 1, 1,10-phenanthroline 2, 3,4,7,8-tetramethyl-1,10-phenanthroline 3, or 4,7-diphenyl-1,10-phenanthroline 4) can be tuned by subtl...

Full description

Bibliographic Details
Main Authors: Suntharalingam, Kogularamanan, Lin, Wei, Lippard, Stephen J., Johnstone, Timothy, Bruno, Peter Michael, Hemann, Michael
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2015
Online Access:http://hdl.handle.net/1721.1/95478
https://orcid.org/0000-0002-2693-4982
https://orcid.org/0000-0003-3383-0118