Synthesis and anticancer activity of epipolythiodiketopiperazine alkaloids

The epipolythiodiketopiperazine (ETP) alkaloids are a highly complex class of natural products with potent anticancer activity. Herein, we report the application of a flexible and scalable synthesis, allowing the construction of dozens of ETP derivatives. The evaluation of these compounds against ca...

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Detaylı Bibliyografya
Asıl Yazarlar: Boyer, Nicolas Cedric, Morrison, Karen C., Kim, Justin, Hergenrother, Paul J., Movassaghi, Mohammad
Diğer Yazarlar: Massachusetts Institute of Technology. Department of Chemistry
Materyal Türü: Makale
Dil:en_US
Baskı/Yayın Bilgisi: Royal Society of Chemistry, The 2015
Online Erişim:http://hdl.handle.net/1721.1/95495
https://orcid.org/0000-0003-3080-1063